Motorcycle Diaries is essentially a Che Guevara biography, with his high-spirited, eight-month journey on a motorcycle. In this biography of Ernesto Che Guevara, Guevara and his dear friend Alberto Granado undertake an exciting journey across Argentina, Chile, Peru, Brazil, Colombia and Venezuela. As a 23-year-old medical student in 1951-52, he mixes lyrical observation, youthful adventure and anti-imperialist political analysis. The Che Guevara biography is as inspiring as it is exciting.

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Flush with a romantic sense of adventure, in this biography of Ernesto Che Guevara, the two friends pile onto Alberto's 1939 Norton 500 motorcycle. The aging bike carries them farther and farther away from familiar and comfortable Buenos Aires surroundings, to surprising and exciting destinations. As the Che Guevara biography continues, the two friends become as close as brothers. From homeless miners to riverboat prostitutes, from lepers to prosperous gentry, Ernesto and Alberto (in this Che Guevara biography) discover an affinity for humanity within themselves and a determination to change the world.

There were many inspiring quotes within the Motorcycle Diaries (a Che Guevara biography). One of the intriguing Che Guevara quotes extracted from the movie was “What do we leave behind when we cross each frontier? Each moment seems split in two; melancholy for what was left behind and the excitement of entering a new land”. Another notable Che Guevara quote was "Often on our travels we longed to stay in some of the wonderful places we saw, but only the Amazon jungle had the same strong pull on the sedentary part of ourselves as this (San Martin) did.”